The Du lab and Lü lab are dedicated to unraveling the complexities of sensory perception—how the human body detects external stimuli, transmits these signals to the brain, and elicits appropriate responses through the intricate network of neuronal ion channels. A particular focus of our work is on understanding the biophysical mechanisms underlying temperature sensation and taste perception. These fundamental aspects of sensory processing offer profound insights into human physiology and potential therapeutic avenues for a range of conditions.