Research Facilities

Scientific Instrument with monitor

Molecular Biosciences researchers and students benefit from shared facilities at Northwestern University and throughout the Chicagoland area. Two of these facilities, the Keck Biophysics Facility and the High Throughput Analysis Facility, are housed within the department. Both facilities have recently undergone major upgrades and renovations, ensuring that they will continue to provide the most comprehensive service and state-of-the-art equipment in their respective fields.

Facility Highlights

Keck Biophysics Facility

The Keck Biophysics Facility, is a unique resource for studying the structures, dynamics and interactions of biological and synthetic macromolecules. This shared research center provides access to a comprehensive collection of 22 research instruments including:

  • Fluorimeters
  • Spectrophotometers
  • Calorimeters
  • Analytical ultracentrifuges
  • Light scattering instruments.

With grants from the W.M.Keck Foundation and additional support from the NIH, the Rice Foundation, and the Robert H. Lurie Comprehensive Cancer Center, the Keck Facility was created by and is housed in Northwestern University's Center for Structural Biology. 

High Throughput Analysis Facility

The High Throughput Analysis Laboratory (HTA) is a shared, open-access resource facility established in 2004; it provides academic, industrial, and private researchers with equipment and expertise for the development and execution of high throughput biological analysis and chemical library screening.

  • The HTA facility is equipped with state-of-the-art robots and instruments for
  • Micro-liter and nano-liter liquid handling
  • Automated microbial culture handling
  • Quantifying target-based phenotypic assays using photometric and radioactive label readouts
  • Automated fluorescence microscopy
  • quantitative imaging analysis for high content screening.

HTA services for users:

  • Designing HTP experiments and data automation,
  • Access to robotic equipment
  • Assistance in grant preparation for HTP-related projects
  • Scientific collaboration in grant proposals containing an HTP component. 
  • Manage on-site access to whole-genome RNAi collections (Open Biosystems) for knockdown of mouse and human gene expression from . 

For a complete description of facility capabilities or to discuss your project, please contact the HTA Laboratory.

Single Cell Genomics Facility

The Single Cell Genomics Facility (SCGF) provides instrumentation and expertise to support experiments involving the isolation and analysis of single cells. This includes flow cytometry and cell sorting, single cell encapsulation and library generation, and spatial transcriptomics.

The facility houses brand-new cutting-edge instrumentation and occupies newly renovated space on the 5th floor of Hogan Hall. The SCGF is run by Interim Director of Operations, Clark Rosensweig, and Faculty Directory, Tom Bozza. A description of available services can be found here, and on NUCORE.

For further information and consultation, please email singlecellgenomicscore@northwestern.edu.

SCGF Logo

Facility List

Research Facilities

Imaging/Cell Imaging Facilities

Structural Biology And Biophysics Facilities