Structural Biology Facility cryo-electron microscopy (cryo-EM) Manager

Northwestern University seeks to recruit an enthusiastic and motivated cryo-electron microscopy (cryo-EM) Facility Manager to join the Structural Biology Facility (SBF), located on the Evanston campus. The successful applicant will be responsible for managing instrumentation and contributing to basic and translational research programs on both the Evanston and Chicago campuses. The SBF cryo-EM facility currently houses a TFS Glacios and JEOL 1400 TEM. In addition, a new TFS Krios G4 will be installed in early 2025. The Glacios is equipped with a Selectrix energy filter and a Falcon 4i direct electron detector. Several instruments for sample preparation are also available as part of the SBF.

Primary Responsibilities:

  • Train and assist users in negative stain and cryo-EM sample preparation, screening, and data collection
  • Contribute to the development and implementation of new EM experimental methods and protocols

Minimum qualifications:

  • Masters or Ph.D. degree with three years of hands-on cryo-EM experience in an EM laboratory.

Preferred qualifications:

  • Ph.D. degree in biochemistry, biology, chemistry, physics or related field
  • Experience in the use of TFS and JEOL microscopes and sample preparation
  • Experience with cryo-EM data collection software (SerialEM and/or EPU) and image processing software packages (Relion, Cryosparc, etc.)
  • Prior experience with different aspects of structural biology research, such as data collection, structure determination, model building, and refinement
  • Excellent technical, teaching, and verbal and written communication skills
  • Ability to work with others and as a team member

This position will report to the Facility Director. Salary commensurate with qualifications and experience.  Northwestern University provides excellent and competitive benefits.

Please submit your CV and ask for 2-3 reference letters to be directly sent to molbiosci@northwestern.edu.  For full consideration, please submit your application by September 15, 2024.

Northwestern University is an Equal Opportunity, Affirmative Action Employer of all protected classes. Women, racial and ethnic minorities, individuals with disabilities, and veterans are encouraged to apply.  Hiring is contingent upon eligibility to work in the United States.